Publications continue to emphasize challenges in implementing the use of GDMT in patients with HF, including suboptimal and delayed initiation of guideline-directed thera-pies and high rates of discontinuation.
Despite the emphasis on timely initiation and optimization of GDMT and planning and counseling for device therapies prior to discharge in hospitalized HF patients, a large number of patients remain untreated.
Heart transplant volumes continue to increase in the US.
The incidence of multi-organ transplantation (ie, heart-kidney, heart-liver, heart-lung) has increased since the 2018 allocation policy change.